INSTRUCTIONS OVERVIEW

STORAGE & HANDLING

DISPOSAL TIPS

STEP 1

MIX

ORANGE CAP UP

SHAKE HARD UP AND
DOWN FOR AT LEAST 15
SECONDS TO DISPERSE
MEDICINE EVENLY¹

COMPLETE

STEP 2

UNLOCK

ORANGE CAP UP

TWIST KNOB FROM LOCK TO UNLOCK¹

ORANGE CAP UP

TWIST KNOB FROM LOCK
TO UNLOCK¹

CLICK

COMPLETE

STEP 3

UNSCREW

ORANGE CAP UP

TWIST ORANGE CAP COUNTERCLOCKWISE¹
DO NOT PULL

COMPLETE

STEP 4

INJECT

IMMEDIATELY INJECT BY PUSHING
AGAINST THE SKIN AND HOLDING FOR
15 SECONDS TO ENSURE A FULL DOSE¹

INJECTION STARTS WHEN AUDIBLE
CLICK IS HEARD¹

IMMEDIATELY INJECT BY
PUSHING AGAINST THE
SKIN AND HOLDING FOR
15 SECONDS TO ENSURE
A FULL DOSE¹

INJECTION STARTS WHEN
AUDIBLE CLICK IS HEARD¹

VIEW INJECTION SITES

CLICK

DONE - IT'S THAT SIMPLE!^2*

EXPLORE DEVICE

VIEW SAVINGS CARD

*In a human factor validation study, most participants, 89 of 104 (85.5%),
rated the complete overall injection task as either "easy" or "very easy."²

*In a human factor validation study,
most participants, 89 of 104
(85.5%), rated the complete
overall injection task as either
"easy" or "very easy."²

WELCOME TO THE BYDUREON BCISE

3D DEVICE SIMULATOR

LEARN TO USE ONCE-WEEKLY BYDUREON BCISE. BYDUREON BCISE IS FOR ADULTS WITH T2D ALONG WITH
DIET AND EXERCISE UNCONTROLLED ON THEIR CURRENT TREATMENT, WHO NEED A GLP-1 RA TO IMPROVE GLYCEMIC CONTROL.¹

LEARN TO USE ONCE-WEEKLY BYDUREON BCISE.
BYDUREON BCISE IS FOR ADULTS WITH T2D ALONG WITH
DIET AND EXERCISE UNCONTROLLED ON THEIR CURRENT TREATMENT,
WHO NEED A GLP-1 RA TO IMPROVE GLYCEMIC CONTROL.¹

FOR COMPLETE INSTRUCTIONS PLEASE SEE INSTRUCTIONS FOR USE.

FOR COMPLETE INSTRUCTIONS,
PLEASE SEE INSTRUCTIONS FOR USE.

START

EXPLORE

BYDUREON BCISE IN 3D

CLICK AND DRAG TO ROTATE THE DEVICE.
USE YOUR MOUSE TO ZOOM IN AND OUT.

SWIPE THE SCREEN TO ROTATE THE DEVICE.
PINCH AND EXPAND TO ZOOM IN AND OUT.

SINGLE DOSE AUTOINJECTOR

BYDUREON BCISE

SAVINGS PROGRAM

BYDUREON BCISE IS THE ONLY GLP-1 RA WITH A $0* SAVINGS OFFER,
FOR ELIGIBLE PATIENTS.

BYDUREON BCISE IS THE ONLY GLP-1 RA WITH A
$0* SAVINGS OFFER, FOR ELIGIBLE PATIENTS.

GET SAVINGS CARD

*SEE ELIGIBILITY REQUIREMENTS. RESTRICTIONS APPLY.

CLICK & DRAG UP OR DOWN
ON THE DEVICE TO MIX

SWIPE UP OR DOWN
ON THE DEVICE TO MIX

SUCCESS = MEDICINE IS MIXED EVENLY AND CLOUDY
IN COLOR. YOU DO NOT SEE ANY MEDICINE ALONG
THE SIDES, BOTTOM OR TOP.¹

SUCCESS = MEDICINE IS MIXED
EVENLY AND CLOUDY IN COLOR. YOU
DO NOT SEE ANY MEDICINE ALONG
THE SIDES, BOTTOM OR TOP.¹

DO NOT PROCEED TO THE NEXT STEP UNTIL
MEDICINE IS WELL-MIXED.¹

DO NOT PROCEED TO THE NEXT STEP
UNTIL MEDICINE IS
WELL-MIXED.¹

CONTINUE
TO STEP 2

CLICK & DRAG LEFT ON
THE DEVICE TO UNLOCK

SWIPE LEFT ON
THE DEVICE TO UNLOCK

SUCCESS = AUDIBLE CLICK SOUND¹

SUCCESS = AUDIBLE CLICK
SOUND¹

CONTINUE
TO STEP 3

CLICK & DRAG RIGHT ON THE
DEVICE TO UNSCREW CAP

SWIPE RIGHT ON THE
DEVICE TO UNSCREW CAP

SUCCESS = ORANGE CAP LIFTS OFF WITHOUT
EFFORT AND GREEN SHIELD POPS UP¹

SUCCESS = ORANGE CAP
LIFTS OFF WITHOUT
EFFORT AND GREEN
SHIELD POPS UP¹

CONTINUE
TO STEP 4

CLICK & DRAG DOWN
ON THE DEVICE
TO INJECT

SWIPE DOWN
ON THE DEVICE
TO INJECT

SUCCESS = ORANGE ROD APPEARS IN
WINDOW, PLUNGER STOPS MOVING AND
DEVICE HAS BEEN HELD FIRMLY AGAINST
SKIN FOR FULL 15 SECONDS¹

SUCCESS = ORANGE ROD
APPEARS IN WINDOW,
PLUNGER STOPS MOVING
AND DEVICE HAS BEEN
HELD FIRMLY AGAINST
SKIN FOR FULL 15
SECONDS¹

VIEW SAVINGS CARD

INJECTION SITES

Weekly injection may use same body part, with new injection site¹

INSTRUCTIONS OVERVIEW

For complete instructions, please see Instructions for Use.

MIX

Shake up and down
for at least 15 seconds
until well mixed¹

UNLOCK

Turn clockwise
to unlock¹

UNSCREW

Unscrew orange cap
counterclockwise¹

INJECT

Inject immediately and
hold for 15 seconds to
get full dose¹

HOW SUPPLIED, STORAGE & HANDLING¹

HOW SUPPLIED,
STORAGE & HANDLING¹

BYDUREON BCise comes in a box with a 4-week supply and full Instructions for Use.

BYDUREON BCise should be stored flat in the refrigerator between 36°F and 46°F
(2°C and 8°C). Protect from light.

BYDUREON BCise may be kept at room temperature, not to exceed 86°F (30°C),
for up to 4 weeks.

BYDUREON BCise comes in a box with a 4-week supply and
full Instructions for Use.

BYDUREON BCise should be stored flat in the refrigerator
between 36°F and 46°F (2°C and 8°C). Protect from light.

BYDUREON BCise may be kept at room temperature, not to
exceed 86°F (30°C), for up to 4 weeks.

DISPOSAL TIPS

Do NOT dispose in household trash¹
Use an FDA-cleared sharps container¹
If not available, use heavy-duty plastic container
with a tight-fitting, puncture-resistant lid¹
Properly label as hazardous waste¹
Follow all state and local disposal laws¹

Do NOT dispose in household trash¹
Use an FDA-cleared sharps container¹
If not available, use heavy-duty
plastic container with a tight-fitting,
puncture-resistant lid¹
Properly label as hazardous waste¹
Follow all state and local disposal laws¹

Visit www.safeneedledisposal.org for more information.

REFERENCES

BYDUREON BCise^® ([exenatide extended-release] injectable suspension)
[prescribing information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2020.
Data on file, REF-14053, AstraZeneca Pharmaceuticals LP.

STEP 1

MIX

STEP 2

UNLOCK

STEP 3

UNSCREW

STEP 4

INJECT

EXPLORE

SAVINGS CARD

STEP 1

STEP 2

STEP 3

STEP 4

WELCOME TO THE BYDUREON BCISE

3D DEVICE SIMULATOR

EXPLORE

BYDUREON BCISE IN 3D

SINGLE DOSE AUTOINJECTOR

BYDUREON BCISE

SAVINGS PROGRAM

INJECTION SITES

INSTRUCTIONS OVERVIEW

HOW SUPPLIED, STORAGE & HANDLING1

HOW SUPPLIED, STORAGE & HANDLING1

DISPOSAL TIPS

REFERENCES

HOW SUPPLIED, STORAGE & HANDLING¹

HOW SUPPLIED,
STORAGE & HANDLING¹